六味葛蓝降脂片大鼠30d喂养试验研究（基础医学范文）.docVIP

六味葛蓝降脂片大鼠30d喂养试验研究（基础医学范文） 文档信息 主题： 关于“行业资料”中“系统集成”的参考范文。 属性： F-00NZVJ，doc格式，正文4932字。质优实惠，欢迎下载！ 适用： 作为文章写作的参考文献，解决如何写好实用应用文、正确编写文案格式、内容摘取等相关工作。 作者： 佚名 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 搞要 1 关键字：六味葛蓝降脂片；毒理学安全性；实验研究 2 1 材料与方法 3 2 结果 5 3 讨论 6 [参考文献] 7 [12] .食品安全性毒理学评价程序[S] 8 [14] 天和60天喂养试验[S] 8 论文原创声明（模板） 10 论文致谢（模板） 10 正文 六味葛蓝降脂片大鼠30d喂养试验研究（基础医学范文） 搞要 摘要：目的通过大鼠30d喂养试验，探讨六味葛蓝降脂片的安全性。方法选取80只大鼠，随机分为3个剂量组和1个对照组（共4组），每组20只，雌、雄各10只。剂量组给予、、g/（kg?BW）的剂量（人体可能摄入量的150、100、50倍），对照组灌服等体积蒸馏水，每天灌胃1次，连续30d后对大鼠各项指标进行观察。结果各剂量组与对照组在试验过程中均生长良好，无死亡，未发现异常体征。各剂量组的体重增长率、食物利用率、血液学指标、血液生化指标、脏/体比值等指标与对照组比较，差异无统计学意义（P）。结论在本实验的剂量范围内，六味葛蓝降脂片大鼠30d喂养未见短期的毒副作用 关键字：六味葛蓝降脂片；毒理学安全性；实验研究 [中图分类号] R-332 [文献标识码] A [文章编号] 1674-4721（2016）03（c）-0015-04 [Abstract] Objective To explore the safety of Liuwei Gelan Lipid-decreasing tablet by 30-day feeding in rats. Methods 80 rats were selected and randomly divided into 3 groups with dosages and the control and female rats were equally these dosage groups，， and g/（kg?BW） were provided，which were 150，100 and 50 times of dosages taken by human the control group，the same volume of distilled water was was performed once per each index from rats was observed and tested after 30 continuing days of experiment. Results Rats were all well grown without death in the process of experiment in the control group and each dosage abnormal sign was was no significant difference in the weight growth rate，food utilization rate，haematological inde，hematologic and biochemical indices，viscera/body ratio between these among 3 dosage groups and the control group （P）. Conclusion Within dosages tested in the experiment，no short-term toxic and side effect is detected after 30-day feeding in rats by Liuwei Gelan Lipid-decreasing tablets. [Key words] Liuwei Gelan Lipid-decreasing tablet；Toxicological safety；30-day feeding 高脂血症（hyperlipaemia，HLP）是一种常见病、多发病，常诱发冠心病、动脉硬化、脂肪肝、糖尿病、肥胖等症，严重危害人类的身体健康。随着人们生活水平的不断提高和社会人口老龄化，高脂血症的发病率呈明显上升和年轻化趋势。目前，用于治疗高脂血症的西药（如他