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降级治疗的临床意义1降阶治疗的临床证据2帮助降级治疗的策略3 2014GINA强调哮喘是一种异质性疾病Asthma is a heterogeneous disease, usually characterized by chronic airway inflammation. It is defined by the history of respiratory symptoms such as wheeze, shortness of breath, chest tightness and cough that vary over time and in intensity, together with variable expiratory airflow limitation.1. Busse ww. Lemanske RF. N Engl J Med 2001,244:350-362. 2. Lushin AT. J Allergy Clin immunol 2005, 115 s539-s545哮喘具有变异性和波动性特征12111098761 4 7 10 13 16 19 22 25 28 31 34 37 40 43 46 49 53周Schreurs JM et al. ERS 2003
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