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International Journal of Psychiatry and Neurology 国际神经精神科学杂志, 2019, 8(4), 31-40
Published Online November 2019 in Hans. /journal/ijpn
/10.12677/ijpn.2019.84006
A Study on the Status of Psychobehavioral
Symptoms in Patients with Alzheimer’s
Disease
1*# 2 1
Yongmei Hou , Peicheng Hu , Simin Mai
1
Department of Psychology, School of Humanity and Administration, Guangdong Medical University,
Dongguan Guangdong
2
Department of Medical Psychology, Medical College of Peking University, Beijing
th nd th
Received: Nov. 8 , 2019; accepted: Nov. 22 , 2019; published: Nov. 29 , 2019
Abstract
Objective: To investigate the incidence and correlation of psychobehavioral symptoms in the outpa-
tients with Alzheimer’s disease (AD). Method: One hundred sixty-two elderly AD outpatients were
randomly selected from Sanjiu brain Hospital of Guangdong Province for general investigation, and
Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment, Beijing version of MOCA,
were used. Severe Impairment Battery (SIB) and Alzheimer’s Disease Assessment Scale-Cognitive
subscale (ADAS-Cog) were conducted to determine the severity of cognitive dysfunction, and Neu-
ropsychiatric questionnaire (NPI) was conducted to evaluate the patients’ mental and behavioral
symptoms and the difficulty of care. Results: 1) In the 162 patients, 35 had mild dementia (21.6%), 44
moderate dementia (27.2%), 54 severe dementia (33.3%), and 29 severe dementia (17.9%). 2) Of
162 dementia patients, 154 patients had at least one mental or behavioral s
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