大肠癌的护理查房PPT课件.ppt

Association Between genotype Status and Response to 5-FU base Chemotherapy in 173 Patients With advanced Gastric Cancer（2002－2008） Overall frequency Responder p-value No. of Pts % No. of Pts RR(%) MTHFR C677T C/C 55 31.8 13 23.6 0.000 C/T 88 50.9 27 30.7 T/T 30 17.3 22 73.3 MTHFR A1298C A/A 122 70.5 51 41.8 0.011 A/C 49 28.2 11 17.7 C/C 2 1.2 0 0.0 TS 28bp in 5`UTR 2R/2R 8 5.9 2 25.0 0.487 2R/3R 40 29.6 18 45.0 3R/3R 87 64.4 32 36.8 TS 6bp in 3`URT -6bp/-6bp 65 37.6 25 38.5 0.044 -6bp/+6bp 74 42.8 31 41.9 +6bp/+6bp 34 19.7 6 17.6 RR: response rate. * 1 西妥昔单抗联合FOLFIR I方案治疗晚期大肠癌的临床观察 2006 年6 月～2