MRS的原理和临床应用.ppt

The acute multiple sclerosis (Fig 4) plaques may produce large mass effect with surrounding edema and blood-brain barrier rupture (pseudotumoral multiple sclerosis lesions), at times simulating neoplasm, in particular when there is only one lesion. In proton MRS they are characterized by lac increase,depending on the degree of inflammatory reaction, and by increased Cho/Cre ratios due to acute myelin break down, but usually not so intense as in neoplastic lesions. Chronic plaques present reduced NAA/Cre ratios in the center of the lesion, as consequence of irreversible axonal injury and part