三核苷酸重复与人类疾病.ppt

三核苷酸重复与人类疾病Trinucleotide repeats and human disorder; 简介（INTRODUCTION ）;三核苷酸重复带来人类疾病特点characteristics of disorders caused by trinucleotide repeat;3.重复在非编码区域降低转录和翻译 （Repeats in non-coding regions - reduced transcription or translation）; ; ;重复在非编码区域改变RNA功能;三核苷酸重复种类（按照其相对位置）Category of the trinucleotide repeat (based on the relative location);;三核苷酸重复在非编码区（Repeats in non-coding sequences）;不编码的三核苷酸重复带来疾病的特点NON-CODING TRINUCLEOTIDE REPEAT DISORDERS;脆性X染色体 Fragile X syndrome;脆性X染色体基因型种类genotype of Fragile X syndrome;脆性X染色体Fragile X syndrome (FRAXA);Fragile X syndrome (FRAXA);Fragile X syndro