综合干预措施对慢性阻塞性肺病的临床意义.docVIP

综合干预措施对慢性阻塞性肺病的临床意义 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：综合干预措施对慢性阻塞性肺病的临床意义 1 1 资料与方法 2 2 结果 3 3 讨论 4 文2：慢性阻塞性肺病的药物治疗 5 (1)非吸入途径使用的药物 6 参考文摘引言： 10 原创性声明（模板） 12 文章致谢（模板） 12 正文 综合干预措施对慢性阻塞性肺病的临床意义 文1：综合干预措施对慢性阻塞性肺病的临床意义 Abstract： Objective To improve the quality of life and to decrease the frequency of acute exacerbation in the patients with chronic obstructive pulmonary disease (COPD).Methods Clinical data of 100 patients, who met the requirements as indicated in the guidelines of COPD published by Respiratory Division of Chinese Medical Association, were collected and divided into two groups at random. One group (trial group) was administered systemic intervention, including COPD education, pneumonia vaccine injection, direct itruction and coultation from docto, inhalation of budesonide (400 μɡ/d) and formoterol (9-18 μɡ/d), and so on. The other group (control group) was given the medication only on the patients basic demand, and didnt receive systemic intervention. Results There existed a group difference in smoking abstinence rate: 80% in the trial group and 20% in the control group (P). The frequency of acute exacerbation decreased in the trial group and its hospitalization rate went down from % (before intervention) to % (P). The group difference was also manifested in hospital stay length (±5 vs. ±3 days, P). The quality of life was significantly improved in the trial group as compared with that in the control group (P).Conclusion Systemic intervention is of importance for the patients with COPD. Key words： chronic obstructive pulmonary disease; systemic intervention; pulmonary function; life quality 慢性阻塞性肺病（COPD）是一种发病率较高的呼吸道慢性疾病，其急性加重期的病死率高，严重危害人们的健康，因此，延缓COPD患者病情进展，对提高其生活质量有重大意义。2005年3月—2006年3月我们对100例COPD患者进行了综合干预处理，现将结果 总结 报告如下。 1 资料与方法 一般情况 100例COPD患者均来自本院门诊，男性72例，女性28例，年龄50～80岁，平均67岁，随机分为两组，观察组和对照组各50例。 选择标准 COPD的诊断及分级按2002年慢性阻塞性肺病诊治指南标准，临床严重度分级[1]，按1 s 用力呼气容积（FEV1）占预计值的百分比（FEV1%），分为轻、中、重三级。Ⅰ级（轻度）FEV1/FVC70%，FEV1≥80%预计值，Ⅱ级（中