决明子的不同提取物及炮制品对四氯化碳致小鼠急性肝损伤的保护作用药学.docVIP

决明子的不同提取物及炮制品对四氯化碳致小鼠急性肝损伤的保护作用药学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：决明子的不同提取物及炮制品对四氯化碳致小鼠急性肝损伤的保护作用药学 1 1 器材 3 2 方法与结果 3 3 讨论 6 文2：黄翅大白蚁菌圃对四氯化碳所致小鼠急性肝损伤的保护作用药学 6 1 材料与仪器 8 2 方法 8 3 结果 9 4 讨论 10 参考文摘引言： 11 原创性声明（模板） 12 文章致谢（模板） 12 正文 决明子的不同提取物及炮制品对四氯化碳致小鼠急性肝损伤的保护作用药学 文1：决明子的不同提取物及炮制品对四氯化碳致小鼠急性肝损伤的保护作用药学 Abstract：ObjectiveTo investigate the protective effects of different extracts and processed products of Semen Cassiae on the acute liver injury induced by CCl4. MethodsKM mice were divided into normal group, control group, biphenyl dimethylester group ( g/kg) and Semen Cassiae group (11g crude drug/kg), which were processed by intragastric administration for 9 days. %CCl4 oil solution (10 ml/kg, diluted with plant oil) was injected into the mice of all groups but normal group by intraperitoneal injection 10hr after last administration. The contents of ALT and AST in the serum were determined by chromatometry 16hr after administration of CCl4. ResultsThe five kinds of extracts extracted by different heteropolarity dissolvents but ligarine extract, the free and conjugated anthraquinones significantly decreased the activities of aminopherase. The processed products of Semen Cassiae, the crude and the parched, significantly decreased the activities of aminopherase too. The effect of the crude on the decrease of aminopherase activities was prior to the parched slightly. ConclusionAll of the anthraquinones in Semen Cassiae was the primary active component at the protective effects on liver and decrease of the aminopherase activities and there would be other active components besides all anthraquinones. The follow-up of active components in other extracts but ligarine extract would be urgent at protective effects on liver in the future. The crude may be optimal between two processed products of semen cassiae if Semen Cassiae is used for the protective aim on liver and decrease of aminopherase activities. Key words：Semen cassiae； Ext