补肺片抗炎止咳作用的实验研究.docVIP

补肺片抗炎止咳作用的实验研究 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：补肺片抗炎止咳作用的实验研究 1 1 材料与仪器 3 2 方法［5］ 3 3 结果 5 4 讨论 6 文2：金果榄抗炎作用的实验研究 7 1 材料与仪器 7 2 方法和结果 8 3 讨论 10 参考文摘引言： 10 原创性声明（模板） 11 文章致谢（模板） 12 正文 补肺片抗炎止咳作用的实验研究 文1：补肺片抗炎止咳作用的实验研究 Abstract：ObjectiveTo observe the anti-inflammatory and antitussive effects of Bufei tablets. MethodsThe methods of making ear swellingby xylene and capillary permeability were used to observe the effect of Bufei tablets on acute inflammation in mice. The method of subcutaneous implantation of granuloma formation by cotten observe the effect of Bufei tablets on chronic inflammation in mice. The method of concentrated ammonia inducing cough and mouse excretion of phenol red was used to observe the effect of Bufei tablets. ResultsBufei tabletsin high, middle, low dose groups of xylene-induced ear edema had no inhibitory effect (P); Bufei tablets in high,middle dose groups significantly inhibited mice capillary permeability of acute inflammation. Bufei tablets in high-dose group significantly inhibited mice subcutaneous granuloma chronic anti-inflammatory (P). The frequency of cough and latent period of cough caused by strong ammonia and the excretion of phenol red in the airway of mice with was significantly inhibited by Bufei tablets（P）.ConclusionBufei tablets have the effects of anti-inflammation, reducing sputum and relieving cough and enhancing the immunocompetence of the body. Key words：Bufei tablets； Anti-inflammation； Antitussive 肺气虚证是慢性阻塞性肺疾病（chronic obstructive pulmonorg disease COPD，简称为慢阻肺）常见证候，是一种以气流受限为特征的疾病，其气流受限不完全可逆，是进行性 发展 ，与肺部对有害气体或有害颗粒引起的异常炎症有关［1］，是一种破坏性的肺部疾病，临床上以咳嗽、咯痰、胸闷等为主症。根据COPD的病理特征， 治疗 方法主要是辨证论治，治则可概括为祛邪扶正，活血化淤、化痰降气、急则治标，缓则治本或标本兼治。运用中医药治疗COPD具有较好的疗效，尤其是稳定期患者，中医药治疗具有改善症状，减少发作次数，提高免疫功能，而且有不良反应小的优点。根据中医理论，研制出一种中成药制剂—“补肺片”。该药采用扶正固本的传统方剂“玉屏风散”为基础，另加补肺益气，化痰止咳的多种中药及蛤蚧等配制而成。历年来我们应用本药防治具有肺气虚证的COPD病人五百多例，总有效率达85%以上。药理实验证实：“玉屏风散”对体液免疫有调节作用［2］，对流感病毒有抑制作用［3］和有抗细菌粘附作用［4］。我们多年来采用“补肺片”防治肺气虚证的COPD病人，取得较好疗效，