食管鳞癌组织中HIF1α及FHIT蛋白的表达及意义临床医学（临床医学资料）.doc

食管鳞癌组织中HIF1α及FHIT蛋白的表达及意义临床医学（临床医学资料） 文档信息 主题： 关于“医学心理学”中“肿瘤学”的参考范文。 属性： F-01NHTE，doc格式，正文23866字。质优实惠，欢迎下载！ 适用： 作为医学资料、临床医学资料写作的参考文献，解决如何写好实用应用文、正确编写文案格式、内容摘取等相关工作。 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：食管鳞癌组织中HIF1α及FHIT蛋白的表达及意义临床医学 2 1 资料与方法 3 2 结果 4 3 讨论 5 文2：食管鳞癌组织中HIF1α及Fascin蛋白的表达 6 1 资料与方法 8 2 结果 9 3 讨论 9 参考文摘引言： 12 原创性声明（模板） 13 文章致谢（模板） 14 正文 食管鳞癌组织中HIF1α及FHIT蛋白的表达及意义临床医学（临床医学资料） 文1：食管鳞癌组织中HIF1α及FHIT蛋白的表达及意义临床医学 [ABSTRACT] Objective: To study the expressio of HIF1α and FHIT protein in esophageal squamous carcinoma tissue. Methods: By using SP method of immunohistochemical technique, the expression of HIF1α and FHIT protein in 48 specime of esophageal squamous carcinoma tissue and its corresponding adjacent tissu were detected, and their relatiohip with clinicopathological characteristics were analyzed. Results: The positive expression inteity of HIF1α in esophageal squamous carcinoma tissue was remarkably stronger than that in its corresponding adjacent tissue (P),while the expression inteity of FHIT protein was weaker in esophageal squamous carcinoma tissue (P).There was negative correlation between the positive expression rate of HIF1α protein and that of FHIT protein in esophageal squamous carcinoma tissue(P，r=-). The expression of HIF1α and FHIT protein in esophageal squamous carcinoma tissue were correlated with the invasion depth (pTNM tumor stage) and lymph node metastasis (P)，and the expression of HIF1α was correlated with the differentiation of tumo (P)，but had no correlation with age and gender(P).Conclusio: The abnormal expressio of HIF1α and FHIT protein in esophageal squamous carcinoma tissue suggest that they probably play some roles in the origin and development of esophageal squamous carcinoma，and it reflects the differentiation and invasive potential of esophageal squamous carcinom tissues to same is significant correlation between the expression of HIF1α and determination of FHIT may help in