子宫内膜异位症和子宫腺肌病P450arom和COX2mRNA的表达及意义医学（医学资料）.docVIP

子宫内膜异位症和子宫腺肌病P450arom和COX2mRNA的表达及意义医学（医学资料） 文档信息 主题： 关于“医学心理学”中“妇产科学”的参考范文。 属性： F-01L7R2，doc格式，正文28198字。质优实惠，欢迎下载！ 适用： 作为医学资料、医学资料写作的参考文献，解决如何写好实用应用文、正确编写文案格式、内容摘取等相关工作。 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：子宫内膜异位症和子宫腺肌病P450arom和COX2mRNA的表达及意义医学 2 1 资料和方法 3 1．1 一般资料 3 1．2 主要试剂 4 1．3 方法 4 2 结 果 5 3 讨 论 6 文2：基质金属蛋白酶2mRNA在子宫内膜异位症中的表达及意义医学 8 1 材料与方法 10 2 结果 12 3 讨论 13 参考文摘引言： 15 原创性声明（模板） 17 文章致谢（模板） 17 正文 子宫内膜异位症和子宫腺肌病P450arom和COX2mRNA的表达及意义医学（医学资料） 文1：子宫内膜异位症和子宫腺肌病P450arom和COX2mRNA的表达及意义医学 ［ABSTRACT］ObjectiveTo study the mRNA expressio of aromatase cytochrome P450 and cyclooxygenase2 (COX2) in endometriosis (EMs) and adenomyosis (AM) and their correlation with the diseases. MethodsThe expression of P450arom mRNA and COX2 mRNA were assessed by RTPCR in 22 cases of normal endometrium, 42 of EMs and 33 of AM including the eutopic and ectopic endometrium. The correlation between the mRNA expressio were analyzed. ResultsP450arom mRNA was expressed both in eutopic and ectopic endometrium of EMs and AM. But in normal endometrium, P450arom mRNA expression was not found. The difference between them was significant (F=, q=，P＜). The P450arom mRNA expressio in ectopic endometrium of EMs and AM were significantly higher than that in eutopic endometrium (q＝,；P＜, ). COX2 mRNA was not or weakly expressed in normal endometrium, but it, in ectopic and eutopic endometrium of EMS and AM, significantly upregulated compared with normal endometrium (F=，q=，P＜). Furthermore, the expression of COX2 mRNA in secretory phase was significantly higher than in proliferative phase in normal endometrium and EMs (t=,P＜). No significant changes of COX2 mRNA expression were found throughout the metrual cycle in AM. The COX2 mRNA expressio in ectopic endometrium of EMs and AM were significantly higher than that in eutopic endometrium （q=,;P＜）. There were no correlation between the mRNA expressio of 450arom and COX2 in EMs，and rAFS phases. There