- 1、本文档共126页,可阅读全部内容。
- 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
查看更多
中医基础理论:7-学生用气血津液
* Next, I will present some results about the phase II clinical trials for CP in US. The phase II clinical trials for CP have been conducted in United States since 2008, and the result has been published by FDA of US on December in 2009. Totally 124 moderate chronic stable angina patients were enrolled in the phase II clinical trials. The results demonstrated that 187.5mg Dantonic? administered in a twice daily dosing regimen provided a significant therapeutic benefit on treadmill excise duration relative to placebo at trough on both the end of week 4 and week 8. the frequency of weekly angina decreased significantly in CP treatment group. * the changes in weekly on-demand nitrate intake on CP administration, which decreased in both high and low dose CP group. the safety of CP was also evaluated during the whole clinical trials. Compared to placebo, the rate of side effects, such as CHD symptoms, fatigue, headache, and indigestion, occurred much less at two CP dose groups. On the basis of the phase II clinical trials for CP, EOP2 meeting was held on July 23~24th in 2010 and a special protocol assessment is granted for the upcoming Phase III studies. * * * First of all, I will introduce the Cerebralcare Granule? briefly. I will use CG to stand for it in the following. CG is a newly developed compound Chinese Medicine which was approved in 1996 by the China State FDA for treatment of headache and dizziness associated with cerebrovascular diseases. CG is composed of eleven herbs. * * We first investigated the role of pre-treatment with CG in attenuating global cerebral microcirculatory disturbance and neuron injury in hippocampus CA1. cerebral global I/R was induced in Mongolian gerbils by clamping bilateral carotid arteries for 30 min followed by reperfusion. Different dosage of cerebralcare granule was administrated by gavage 120 minutes before ischemia, and the microcirculatory dynamics was observed continuously. * * This slide show the time courses of
文档评论(0)