脑脊液流空效应对正常压力性脑积水的诊断及预后临床分析（临床医学论文资料）.docVIP

脑脊液流空效应对正常压力性脑积水的诊断及预后临床分析（临床医学论文资料） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：脑脊液流空效应对正常压力性脑积水的诊断及预后临床分析 1 1 临床资料 3 2 讨论 4 3 结论 5 文2：脑脊液实验室检查对颅内感染的诊断价值 5 1 资料与方法 6 2 结果 7 3 讨论 8 参考文摘引言： 9 原创性声明（模板） 11 文章致谢（模板） 11 正文 脑脊液流空效应对正常压力性脑积水的诊断及预后临床分析（临床医学论文资料） 文1：脑脊液流空效应对正常压力性脑积水的诊断及预后临床分析 【Abstract】ObjectiveTo provide a reliable imaging evidence for the diagnosis and prognosis of normal pressure hydrocephalus. MethodsFind the relation between some of the characteristic change in magnetic resonance imaging（MRI）and the diagnosis and prognosis through reviewing the clinical and imaging (mainly MRI) data the patients with ventriculo-peritoneal shunt in 31 cases of normal pressure hydrocephalus， and following-up the of patients’ prognosis for 6 months to 3 yea. ResultsIn 31 cases of normal pressure hydrocephalus patients，there were the excellence in 16 cases (%)， the effective in 9 cases (%)， the ineffective in 6 cases (%)， and the total effective rate was % after operation; in MRT2 weighted graph， there were CSF ow void effect in 13 cases (%) in the aquaeduct cerebrir and the adjacent third ventricle or four intraventricular， of which the excellence in 10 cases (%)， the effective in 3 cases (%)， and the total effective rate was 100%. Conclusion It was a reliable imaging evidence that finding the CSF flow void effects in the aquaeduct cerebrir and the adjacent third ventricle or four intraventricular in MRT2 weighted graph was the diagnosis and better prognosis of the patients with normal pressure hydrocephalus. 【Key words】Flow void effect;Normal pressure; Hydrocephalus; Diagnosis and prognosis 正常压力性脑积水(NPH)是一种以步态或平衡障碍、认知功能减退、尿失禁三联征为主要临床特征，影像上表现为脑室扩大而脑脊液压力正常，经脑脊液分流后可以改善症状的综合征[1]。由于NPH发病较为缓慢，老年人多见，并且临床表现与其他表现为痴呆的疾病重叠，导致诊断、鉴别诊断的困难。NPH目前最有效的治疗方法为脑脊液分流术[2]，一般以侧脑室-腹腔分流术为首选。从手术效果来看，平均颅内压波幅增高者行手术分流治疗，临床症状改善较为明显[3]。所以能为正常压力性脑积水的诊断及预后提供一个可靠的影像学依据具有一定的临床意义。我科自2005-01～2010-12共收治了31例正常压力性脑积水患者，对其临床资料、影像学（主要是MRI）资料回顾性分析，并随访6个月-3年，找出MRI中一些特征性变化与诊断及较好预后的关系，现报告