浅析莫西菌素在畜牧业中的进展（畜牧业论文资料）.docVIP

浅析莫西菌素在畜牧业中的进展（畜牧业论文资料） 文档信息 ： 文档作为关于“研究报告”中“制药行业”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文10567字，doc格式，可编辑。质优实惠，欢迎下载！ 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：浅析莫西菌素在畜牧业中的进展 1 1 莫西菌素的研究概况 3 2 莫西菌素药效学研究 5 3 莫西菌素耐药性研究 11 4 小结 12 文2：神经肽Y应用于畜牧业的研究进展 12 1　神经肽Y在调节畜禽采食量和采食行为方面的应用 12 2　神经肽Y在调节畜禽生长发育方面的研究 13 3　神经肽Y在调节畜禽生殖方面的研究进展 14 参考文摘引言： 15 原创性声明（模板） 15 文章致谢（模板） 16 正文 浅析莫西菌素在畜牧业中的进展（畜牧业论文资料） 文1：浅析莫西菌素在畜牧业中的进展 Abstract：Moxidectin (MOX) is derived from derivatization of nemadectin produced by Streptomyces (Cyanneogrise noncyanogenus) ， which has good iect repellent activity and is safe for mammals， and it is mainly used in animal has better fat-soluble and wateoluble than other avermectin drugs， and has the highest distribution in adipose tissues of binds to GABA， and neural membrane potential hyperpolarization is caused by massive influx of Cl-， resulting in the death due to the iects body in the route of administration and the physiological condition of animals would affect the peak concentration and depletion has good iect repellent activity in animals such as cattle， sheep and application range of moxidectin gradually expands from mammals to birds， and the control objects gradually extend from nematodes to mite and several kinds of research direction extends from anthelmintic activity to the treatment of human the increase of the application range of moxidectin and the prolongation of time， the drug resistance began to appear， and the rate of drug resistance could be reduced by the combination of moxidectin and other the wider role of moxidectin requires the efforts of researche in different fields。 Keyword：moxidectin; pharmacokinetics; pharmacodynamics; drug resistance; 莫西菌素 (moxidectin， MOX) 是第三代阿维菌素类药物， 是由链霉菌 (Streptomyces， Cyanneogrise noncyanogenus) 发酵产生的奈马菌素 (nemadectin) 经化学修饰或衍生而来的结构单一的大环内酯类抗生素[1]， 作为驱虫药物应用在畜牧业中[2]。与其他阿维菌素类药物相比， 具有较高的驱虫活性及安全特性[3] 1 莫西菌素的研究概况 理化性质 与其他阿维菌素类药物和奈马菌素相比， 莫西菌素在C23位上是肟醚取代基， C13位上少一个二糖基， C2