联合检测β HCG倍增率孕酮对甲状腺功能正常孕妇先兆流产治疗效果的预测价值.docxVIP

联合检测β HCG倍增率孕酮对甲状腺功能正常孕妇先兆流产治疗效果的预测价值 联合检测β-hcg倍增率、孕酮对甲状腺功能正常孕妇先兆流产治疗效果的预测价值 　　[摘要]目的探讨联合检测β-hcg倍增率、孕酮对甲状腺功能正常孕妇先兆流产治疗效果的预测价值。方法回顾性分析2018年1～12月在我院诊断治疗的甲状腺功能正常的先兆流产孕妇100例患者。根据治疗结果分为妊娠成功组（74例）与妊娠失败组（26例）。比较两组入组时β-hcg、孕酮水平，治疗后β-hcg倍增率。分析联合检测β-hcg、孕酮对先兆流产治疗的预测价值。结果（1）妊娠成功组入组时β-hcg水平、孕酮水平及治疗后β-hcg倍增率均显著高于妊娠失败组，差异有统计学意义（p0.05）。（2）β-hcg倍增率、孕酮单独检测灵敏度、阴性预测值差异无统计学意义（p0.05）;联合检测的灵敏度、特异度、阴性预测值显著高于β-hcg倍增率、孕酮单独检测，差异有统计学意义（p0.05）。联合检测阳性预测值有所提高，高于孕酮单独检测（p0.05），但与β-hcg倍增率比较差异无统计学意义（p0.05）。结论联合检测β-hcg倍增率、孕酮对甲状腺功能正常孕妇先兆流产治疗效果具有较好的预测作用。 　　[关键词]β-hcg;倍增率;孕酮;先兆流产 　　[中图分类號]r714.21[文献标识码]b[文章编号]1673-9701（2019）34-0065-04 　　valueofcombineddetectionofβ-hcgmultiplicationrateandprogesteroneforpredicationoftreatmenteffectonthreatenedabortioninpregnantwomenwithnormalthyroidfunction 　　liqiong1zhouxiao1xuhaigeng1lujinfei2zhangxia1chenyanjie1 　　1.departmentofobstetricsandgynecology，zhoushanmaternalandchildhealthhospitalinzhejiangprovince，zhoushan316000，china;2.departmentofultrasound，zhoushanmaternalandchildhealthhospitalinzhejiangprovince，zhoushan316000，china 　　[abstract]objectivetoinvestigatethevalueofcombineddetectionofβ-hcgmultiplicationrateandprogesteroneforthepredictionoftreatmenteffectonthreatenedabortioninpregnantwomenwithnormalthyroidfunction.methodsaretrospectiveanalysisof100pregnantwomenwithnormalthyroidfunctionwhowerediagnosedwiththreatenedabortionandtreatedinourhospitalfromjanuarytodecember2018wereperformed.accordingtothetreatmentresults，thesepregnantwomenweredividedintothepregnancysuccessgroup（74women）andthepregnancyfailuregroup（26women）.theβ-hcgandprogesteronelevelsatenrollmentandtheβ-hcgmultiplicationratesaftertreatmentwerecomparedbetweenthetwogroups.thevalueofcombineddetectionofβ-hcgandprogesteroneforthepredicationoftreatmenteffectonthreatenedabortionwereanalyzed.results（1）thelevelsofβ-hcgandprogesteroneatenrollmentandtheβ-hcgmultiplicationrateaftertreatmentinthesuccessfulpregnancygroupweresignificantlyhigherthanthoseinthepregnancyfailuregroup，withsta