比伐卢定联合替格瑞洛治疗ST段抬高型心肌梗死患者的临床研究（基础医学范文）.docVIP

比伐卢定联合替格瑞洛治疗ST段抬高型心肌梗死患者的临床研究（基础医学范文） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：比伐卢定联合替格瑞洛治疗ST段抬高型心肌梗死患者的临床研究 2 1 资料与方法 3 1.1一般资料 3 1.2 方法 4 1.3 观察指标 4 1.4 统计学方法 4 2.1 两组PPCI治疗后心肌梗死溶栓试验血流分级比较 5 2.2 两组治疗后1个月内的主要心血管不良事件发生率比较 5 2.3 两组治疗后不良反应 5 文2：替格瑞洛联合比伐卢定对STEMI急诊PCI无复流临床研究 9 1对象与方法 10 1.1研究对象 10 1.2研究方法 10 1.3观察指标 10 1.4数据录入及统计学处理 11 2.1术后两组TIMI血流分级比较 11 2.2给药前后两组CTFC比较 12 2.3两组无复流率的比较 12 2.4两组术后不良反应情况 12 参考文摘引言： 13 原创性声明（模板） 15 文章致谢（模板） 15 正文 比伐卢定联合替格瑞洛治疗ST段抬高型心肌梗死患者的临床研究（基础医学范文） 文1：比伐卢定联合替格瑞洛治疗ST段抬高型心肌梗死患者的临床研究 Clinical study of bivalirudin combined with ticagrelor in patients with ST - elevation myocardial infarction JIANG Yang ZHENG Xiaoqun Ward 4 of Department of Cardiology， Dalian Municipal Central Hospital， Dalian 116000，China [Abstract] Objective To investigate the clinical effect of bivalirudin combined with ticagrelor on elderly patients with ST-segment elevation myocardial infarction（STEMI）. Methods A retrospective analysis of 140 elderly （≥60 yea） STEMI （segment elevation myocardial infarction）patients undergoing primary percutaneous coronary intervention （PPCI） hospitalized in Dalian Central Hospital from June 2016 to September 2017 was conducted. For the two groups， 68 cases in the observation group took preoperative aspirin combined with ticagrelor and intraoperative bivalirudin anticoagulation treatment； 72 patients in control group took preoperative aspirin combined with clopidogrel and intraoperative heparin sodium coagulation treatment. Results The rate of TIMI grade 3（Thrombolysis in Myocardial Infarction，TIMI） in observation group after PPCI treatment was higher than that of control group， the difference was statistically significant （P0.05）. Conclusion The antithrombotic regimen of bivalirudin combined with ticagrelor and aspirin can improve the prognosis of elderly patients with STEMI. [Key words] Ticagrelor； Clopidogrel； Percutaneous coronary intervention； Acute ST-segment elevat