炎琥宁联合干扰素治疗小儿手足口病的临床效果观察（基础医学范文）.docVIP

炎琥宁联合干扰素治疗小儿手足口病的临床效果观察（基础医学范文） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：炎琥宁联合干扰素治疗小儿手足口病的临床效果观察 1 文2：干扰素联合炎琥宁治疗小儿手足口病的临床效果观察 6 一、资料与方法 6 二、结果 7 三、讨论 8 参考文摘引言： 8 原创性声明（模板） 9 文章致谢（模板） 10 正文 炎琥宁联合干扰素治疗小儿手足口病的临床效果观察（基础医学范文） 文1：炎琥宁联合干扰素治疗小儿手足口病的临床效果观察 DOI：10.14163/j.cnki.11-5547.2018.09.061 【Abstract】 Objective To discuss the clinical efficacy of Yanhuning combined with interferon in the treatment of pediatric hand-foot-mouth disease （HFMD）. Methods A total of 90 HFMD children as study subjects were divided by random number table method into Yanhuning group， interferon group and combined group， with 30 cases in each group. Yanhuning group was treated with Yanhuning， interferon group was treated with recombinant human interferon α-2b injection， and combined group was treated with interferon and Yanhuning. Observation and comparison were made on clinical manifestatio （antipyretic time， hand-foot-mouth herpes subsided time and hospitalization time after medication） and clinical efficacy after medication between the three groups. Results Combined group had shorter antipyretic time， hand-foot-mouth herpes subsided time and hospitalization time after medication than Yanhuning group and interferon group， and their difference was statistically significant （P0.05）. Combined group had significantly higher total treatment effective rate as 93.33% than 76.67% in Yanhuning group and 73.33% in interferon group， and their difference was statistically significant （P0.05）. Conclusion Combination of Yanhuning and interferon shows remarkable efficacy in treating pediatric HFMD with rapid oet， and it is ideal medication regimen. 【Key words】 Yanhuning； Interferon； Pediatric hand-foot-mouth disease； Clinical efficacy 手足口病（hand-foot-mouth disease， HFMD）是一种暴发性传染病， 由多种肠道病毒引起， 易感人群多集中于5岁以下儿童， 临床症状多表现为低热、厌食， 且手、足、口部位会出现小疱疹， 部分病情危重患儿如耽误诊治可致死亡[1]。近年小儿HFMD发病率呈现上升趋势， HFMD传染快、感染性强， 在儿童聚居地流行极快， 寻找HFMD有效治疗药物显得尤为重要。但目前临床上尚缺乏治疗小儿HFMD的特效药物。本院采用炎琥宁联合干扰素治疗小儿HFMD， 临床疗效满意， 现报告如下。 1 资料与方