东阳地区儿童沙门菌感染的流行病学调查及耐药性分析（基础医学范文）.docVIP

东阳地区儿童沙门菌感染的流行病学调查及耐药性分析（基础医学范文） 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：东阳地区儿童沙门菌感染的流行病学调查及耐药性分析 2 1 材料与方法 3 1.1 菌种来源 3 1.3 质控菌株 4 1.4 统计学方法 4 2 结果 4 2.1 患儿沙门菌血清型分布 4 2.3 2016年沙门菌属对前3年耐药谱变化情况分析 5 3 讨论 5 文2：儿童血培养阳性标本病原菌分布及耐药性分析 9 1 资料与方法 10 2 结果 10 2. 2 常见病原菌对抗菌药物的耐药性分析 11 3 讨论 11 参考文摘引言： 12 原创性声明（模板） 13 文章致谢（模板） 13 正文 东阳地区儿童沙门菌感染的流行病学调查及耐药性分析（基础医学范文） 文1：东阳地区儿童沙门菌感染的流行病学调查及耐药性分析 [Abstract] Objective To analyze the distribution characteristics and drug resistance of Salmonella isolated from children in the area. Methods The detection status， serological typing and drug resistance to commonly used antimicrobial agents of salmonella isolated from our hospital from January 2013 to December 2016 were retrospectively analyzed. Results A total of 145 strai of salmonella were detected. The male to female ratio of salmonella infection was 1： 1.07， and 73 were detected in infants aged 1-2 yea（50.34%）. 116 strai（80%） were detected in summer and autumn. Compared with that in the previous three yea， the number of cases detected in 2016 nearly doubled. Salmonella resistance rates to ampicillin， ampicilliulbactam， cotrimoxazole， aztreonam and ceftriaxone all significantly improved. No strai with drug resistance to imipenem and ertapenem were detected. The serotypes of salmonella were mainly group B（46.9%） and group D（28.97%）， with mainly salmonella typhimurium and enteritis salmonella serotype， respectively. Conclusion Salmonella in our hospital is mainly isolated from 1-2 yea infant， with high incidence in summer and autumn， and the drug resistance rate shows an increasing trend. Therefore， we must actively carry out research on salmonella resistance mechanism and epidemiological investigation. The antibiotics should be chosen prudently according to the results of drug susceptibility. Childrens families need to develop good hygiene habits and cut off the tramission routes. [Key words] Salmonella；Children；Drug resistance；Surveill