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Global HRAC MOA Classification Working Group Report
Version: June 2, 2020
Executive Summary
The Global Herbicide Resistance Action Committee (HRAC), supported by regional HRACs around the
world, completed its updated to the mode of action classification system on March 1, 2020. Changes
since the last update in 2010 include the addition of 14 new active ingredients, rationalization of chemical
family names, and four new or updated modes of action: inhibition of fatty acid thioesterase (cinmethylin),
inhibition of homogentisate solanesyltransferase (cyclopyrimorate), inhibition of solanesyl diphosphate
synthase (aclonifen), and inhibition of serine-threonine protein phosphatase (endothall).
With this update, Global HRAC will transition from letter to number mode of action codes. Global HRAC
believes a numerical code system is more globally relevant and sustainable compared to English/Latin
letters. In geographies where the Latin alphabet is not used and/or where literacy rates are low, most
everyone understands Hindu-Arabic numerals (including China). Global HRAC considered several
numerical code options but in the end settled on alignment with the WSSA so that there is single
numerical code shared by WSSA and Global HRAC.
Background
At the global HRAC meeting held May 2017 in Denver, Colorado USA, the current state of herbicide
moa/chemical classification was discussed with a recommendation to update the mode of action
classification, specifically:
1) Review and update the list of active ingredients (a.i.s) – including adding new ones
2) Update/revise MOA designations
3) Update/revise chemical classes
4) Recommend changes to the MOA classification code
5) Devise process for annual review and updates
Working Group
Rex Liebl, BASF, RTP NC, USA
Jeff Epp, Corteva, Indianapolis, IN, USA
Hubert Menne, Bayer, Frankfurt, Germany
Bernd Laber, Bayer, Frankfurt, Germany
James Morris, Syngenta, Jealott’s Hil
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