Argadin-DataSheet-生命科学试剂-MCE.pdf

Hotline: 400-820-3792 Inhibitors • Screening Libraries • Proteins www.MedChemE Argadin Cat. No.: HY-P3461 CAS No.: 289665-92-5 分⼦式: C₂₉H₄₂N₁₀O₉ 分⼦量: 674.71 作⽤靶点: Parasite 作⽤通路: Anti-infection 储存⽅式: Please store the product under the recommended conditions in the Certificate of Analysis. BIOLOGICAL ACTIVITY ⽣物活性 Argadin 是⼀种环五肽⼏丁质酶抑制剂。Argadin 抑制⼏丁质酶 B (ChiB)，Ki 值为 20 nM。Argadin 可⽤于杀 菌剂和杀⾍剂的研究。 IC50 Target Ki: 20 nM (ChiB) [2] 体外研究 Argadin has inhibitory activity for chitinase B (ChiB) with a Ki value of 20 nM [2]. REFERENCES [1]. Jun Koseki, et al. Molecular Orbital Study of the Formation of Intramolecular Hydrogen Bonding of a Ligand Molecule in a Protein Aromatic Hydrophobic Pocket. Chem Pharm Bull (Tokyo). 2016;64(7):1031-5. [2]. Hiroaki Gouda, et al. Computational analysis of the binding affinities of the natural-product cyclopentapeptides argifin and argadin to chitinase B from Serratia marcescens. Bioorg Med Chem. 2008 Apr 1;16(7):3565-79. McePdfHeight Caution: Product has not been fully validated for medical applications. For researc