反复应激引起前额叶皮层上谷氨酸受体的表达.pptxVIP

反复应激引起前额叶皮层上谷氨酸受体的表达第1页/共35页 Repeated restraint stress:Juvenile (3- to 4-week-old) Sprague Dawley male rats were used in this study.For repeated restraint stress, rats were placed in air-accessible cylinders for2 hr daily (10:00 a.m. to 12:00 p.m.) for 5–7 days. The container size was similar to the animal size, which made the animal almost immobile in the container.第2页/共35页 Results:To test the impact of stress on cognitive functions, they measured the recognition memory taskRU486: GR antagonist第3页/共35页 To examin whether other stressors could produce a similar effectRepeated unpredictable stre