化浊解毒汤治疗慢性萎缩性胃炎40 例临床观察.docxVIP

第36 卷第5 期 vol. 36 No. 5 .7 .2020 年5 月 HUNANJOURNALOFTRADITIONALCHINESEMEDICINE .7 . 引用：杨情 ,康欣 ,刘建平 ,郎晓猛 ,任杰 ,刘思雨 ,毛若柿 . 化浊解毒汤治疗慢性萎缩性胃炎 40 例临床观察[J]. 湖南中医 杂志 ,2020 ,36(5)：7 - 9. 化浊解毒汤治疗慢性萎缩性胃炎 40 例临床观察 杨 借1 ,康 欣1 ,刘建平1 , 郎晓猛1 ,任 杰1 ,刘思雨2 ,毛若桶2 (1. 河北省中医院 ,河北 石家庄 ,050011；2. 河北中医学院 ,河北 石家庄 ,050091) [摘要] 目的：观察化浊解毒汤治疗慢性萎缩性胃炎(CAG) 的临床疗效及对患者生存质量的影响 。方法：将 80 例慢性 萎缩性胃炎患者随机分为治疗组和对照组 ,每组各40 例 。治疗组予化浊解毒汤治疗 ,对照组予胃复春片治疗 ,2 组疗程均为6 个月 。观察2 组治疗前后中医证候积分、病理组织学分级 ,评定中医证候疗效及病理组织学疗效；采用健康状况调查简表 (SF- 36)对患者治疗前后生存质量进行评价 。结果：中医证候疗效、病理组织学疗效治疗组分别为 92. 5%(37/40) 、80. 0% (32/40) ,对照组分别为77. 5%(31/40) 、55. 0%(22/40) ,2 组比较 ,差异均有统计学意义(P0. 05) 。治疗组在生存质量中躯 体疼痛(BP) 、社交功能(SF) 、情感职能(RE)3 个方面的评分优于对照组 , 差异有统计学意义(P0. 05) 。结论：化浊解毒中 药治疗 CAG临床疗效明显 ,并可提高患者生存质量。 [关键词] 慢性萎缩性胃炎；中医药疗法；化浊解毒汤；生存质量 [中图分类号]R259. 733 + . 2 [文献标识码]A DOI：10. 16808/j. cnki. issn1003 - 7705. 2020. 05. 003 clinical effect of Huazhuo Jiedu decoction in treatment of chronic atrophic gastritis：An analysis of40 cases YANGQian1 ,KANGXin1 ,LIUJianping1 ,LANGXiaomeng1 ,RENJie1 ,LIUSiyu2 ,MAORuonan2 (1. Hebei Provincial Hospital of Traditional Chinese Medicine ,Shijiazhuang050011 ,Hebei ,China； 2. Hebei University of Chinese Medicine ,Shijiazhuang050091 ,Hebei ,China) [Abstract] Objective：To investigate the clinical effect of Huazhuo Jiedu decoction in the treatment of chronic a- trophic gastritis(CAG) and its effect on patients , quality of life. Methods：Atotal of80 patients with CAGwere randomly divided into treatment group and control group ,with 40 patients in each group. The patients in the treatment group were given Huazhuo Jiedu decoction ,and those in the control group were given weifuchun tablets. The course of treatment was6 months for both groups. Traditional Chinese medicine(TCM) syndrome score and histopathological grade were observed before and after treatment to evaluate the outcome of TCM syndrome and histopatholo