人体生物刺激反馈仪对2型糖尿病患者心血管自主神经病变的筛查及相关危险因素分析.docVIP

·2079 · · 论 著 · 人体生物刺激反馈仪对2型糖尿病患者心血管自主神经病变的 筛查及相关危险因素分析 邵侃，黄珊，卢苏梅，汤瑜斌，衡晓湘，裘佳颖，夏莉莉 【摘要】 目的 探讨人体生物刺激反馈仪 (Ezscan) 对2型糖尿病患者自主神经病变的检出情况及相关的危险 因素。方 法 回顾性分析上海市长宁区中心医院内分泌科2011年11月—2012年6月收治的2型糖尿病患者98例，采 用经典实验和 Ezscan检测方法诊断相关患者的心血管神经病变情况。对比两种方法的异常检出率及引起患者发生心血 管自主神经病变的危险因素。 结果 2型糖尿病心血管自主神经病变的经典实验检出率为45%(44/98), Ezscan 检测 为50%(49/98),差异无统计学意义 (Xx2=0.512,P0.05)。 在 Ezscan检测中，异常者较正常者的年龄、病程、腰 围、体质指数 (BMI)、 体脂、血压、肌酐、三酰甘油、肱踝脉搏波传导速度及高血压患病率均更高，且差异有统计学 意义 (P0.05)。 通过 Logistic回归分析发现糖尿病心血管自主神经病变的危险因子为：年龄和BMI。 结论 Ezscan 检 测较经典实验的异常检出率无差异，是一种无创性可定量早期诊断及评估糖尿病自主神经病变程度的手段，为临床诊 治提供新的依据。 【关键词】 糖尿病，2型；人体生物刺激反馈仪；自主神经病变 【中图分类号】 R587.1 【文献标识码】 A doi:10.3969/j. issn.1007-9572.2013.06.083 邵侃，黄珊，卢苏梅，等.人体生物刺激反馈仪对2型糖尿病患者心血管自主神经病变的筛查及相关危险因素分 析 [J]. 中国全科医学，2013,16(6):2079-2081.[] S creen of Cardiac Autonomic Neuropathy by Ezscan Technology in Patients with Type 2 Diabetes and Analysis of Risk Factors SHAO Kan, HUANG Shan, LU Su-mei,et al. Department of Endocrinology,Changning District Central Hospital, Shanghai 200336,China 【Abstract] Objective To study the screen of cardiac autonomic neuropathy by Ezscan in patients with type 2 diabetes mellitus(T2DM)and to analyze related risk factors. Methods 98 T2DM patients admitted to the Department of endocrine of Shanghai Changning District Central Hospital from November 2011 to June 2012 were retrospectively analyzed. Classic experiment and Ezscan were both used to detect cardiovascular autonomic neuropathy. The detection rate of abnormalities and risk factors for cardiovascular autonomic neuropathy were analyzed. Results The detection rate of diabetic cardiovascular autonomic neuropathy by classic experiment and Ezscan was 45%(44/98)and 50%(49/98)respectively,and the difference was not statistically significant (x2=0.512,P0.05).During Ezscan detection, the age, duration, waist circumference,BMI,body fat, blood pressure, creatinine,acyl glycerin, baPWV, peripheral neuropathy and detection rate o