2型糖尿病大血管病变的中医证型与踝肱指数的临床研究的开题报告.docx

2型糖尿病大血管病变的中医证型与踝肱指数的临床研究的开题报告 摘要： 糖尿病是一种多种代谢异常所导致的慢性代谢性疾病，其中2型糖尿病是较为常见的一种类型。2型糖尿病患者往往会出现大血管病变，严重影响患者的生活质量。中医认为，糖尿病主要是由于脾胃虚弱、气血不足、肺肾亏损等内因外因共同作用所致。因此，通过中医辨证施治，可以对2型糖尿病患者的大血管病变进行有效控制。 本研究旨在探讨2型糖尿病大血管病变的中医证型与踝肱指数的关系。通过回顾性研究的方法，首先将糖尿病患者分为大血管病变组和非大血管病变组。然后，对两组患者的体检结果，包括心电图、脉搏波传导速率等进行比较，计算踝肱指数。最后，对大血管病变组患者的中医证型进行分析，比较不同证型与踝肱指数的相关性。 预期结果是，大血管病变组患者的中医证型将呈现出明显的气虚血瘀、阴虚火旺、痰湿内盛等症状。同时，大血管病变组患者的踝肱指数将明显低于非大血管病变组患者。通过对中医证型与踝肱指数的相关性分析，可以进一步明确中医辨证施治在2型糖尿病大血管病变防治中的重要作用。 关键词：2型糖尿病；大血管病变；中医证型；踝肱指数；回顾性研究 Abstract: Diabetes is a chronic metabolic disease caused by multiple metabolic abnormalities. Type 2 diabetes is a common type. Type 2 diabetes patients often suffer from large-vessel disease, which seriously affects their quality of life. Traditional Chinese medicine believes that diabetes is mainly due to the combination of internal and external factors, such as spleen and stomach weakness, insufficient Qi and blood, and lung and kidney deficiency. Therefore, through differentiation and treatment of traditional Chinese medicine, large-vessel disease in type 2 diabetes patients can be effectively controlled. This study aims to explore the relationship between traditional Chinese medicine syndrome differentiation and ankle-brachial index in large vessel disease of type 2 diabetes. By retrospective study, diabetes patients were divided into two groups, large-vessel disease and non-large-vessel disease groups. Then, the results of physical examination, including electrocardiogram and pulse wave propagation rate, were compared, and the ankle-brachial index was calculated. Finally, the traditional Chinese medicine syndrome was analyzed, comparing the correlation between different syndromes and ankle-brachial index in large-vessel disease group. The expected results are that the traditional Chinese medicine syndrome of the large-vessel disease group will show obvious symptoms such as Qi deficiency, blood stasis, Yin deficiency and fire prosperity, and phlegm dampness internal accumulation. At