Milbemycin-A4-DataSheet-生命科学试剂-MCE.pdf

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MilbemycinA4

Cat.No.:HY-126906

CASNo.:51596-11-3

分⼦式:C₃₂H₄₆O₇

分⼦量:542.7

作⽤靶点:Antibiotic;P-glycoprotein

作⽤通路:Anti-infection;MembraneTransporter/IonChannel

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MilbemycinA4抑制P-糖蛋⽩活性，逆转肿瘤细胞的多药耐药性。Milbemycin是⼀类具有杀⾍和杀螨活性的

⼤环内酯类抗⽣素。

REFERENCES

[1].LiJ,etal.IsolationandidentificationofnewmacrocycliclactonesfromageneticallyengineeredstrainStreptomycesbingchenggensis

BCJ60.JAntibiot(Tokyo).2017Mar;70(3):297-300.

[2].TakiguchiY,etal.Milbemycins,anewfamilyofmacrolideantibiotics:fermentation,isolationandphysico-chemicalproperties.JAntibiot

(Tokyo).1980Oct;33(10):1120-7.

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