HER2-IN-17-DataSheet-生命科学试剂-MCE.pdf

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HER2-IN-17

Cat.No.:HY-163418

分⼦式:C₂₈H₂₄N₁₀O₂

分⼦量:532.56

作⽤靶点:EGFR

作⽤通路:JAK/STATSignaling;ProteinTyrosineKinase/RTK

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性HER2-IN-17(Compound2)是HER2抑制剂，可抑制YVMAHER220外显⼦插⼊突变(HER2YVMA)，IC50

IC50[1]。

IC50TargetHer2exon20YVMAinsertion

50)

REFERENCES

[1].SvitlanaKULYK,etal.,Compoundsandmethodsformodulatingher2.PatentWO2024044570.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师