MitoB-bromide-DataSheet-生命科学试剂-MCE.pdf

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Inhibitors•ScreeningLibraries•Proteins

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MitoBbromide

Cat.No.:HY-126474

CASNo.:1247025-84-8

分⼦式:C₂₅H₂₃BBrO₂P

分⼦量:477.14

作⽤靶点:ReactiveOxygenSpecies

作⽤通路:Immunology/Inflammation;MetabolicEnzyme/Protease;NF-κB

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MitoBbromide是线粒体过氧化氢的外切标记物。MitoBbromide是⼀种靶向线粒体的⽐例探针，可⽤于测量

活体动物体内⼀种主要ROS(过氧化氢)的⽔平。

体外研究MitoBisrapidlytakenupbymitochondriaandconvertstoMitoP,whichenablesthequantificationofH2O2

[2].

REFERENCES

[1].SalinK,etal.UsingtheMitoBmethodtoassesslevelsofreactiveoxygenspeciesinecologicalstudiesofoxidativestress.SciRep.

2017Jan24;7:41228.

[2].CocheméHM,etal.Usingthemitochondria-targetedratiometricmassspectrometryprobeMitoBtomeasureH2O2inlivingDrosophila.

NatProtoc.2012Apr19;7(5):946-58.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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