HER2-IN-16-DataSheet-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

HER2-IN-16

Cat.No.:HY-163420

分⼦式:C₂₅H₂₃N₉O₂

分⼦量:481.51

作⽤靶点:EGFR

作⽤通路:JAK/STATSignaling;ProteinTyrosineKinase/RTK

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性HER2-IN-16(Compound14)是HER2抑制剂，可抑制YVMAHER220外显⼦插⼊突变(HER2YVMA)，IC50

IC50[1]。

IC50TargetHer2exon20YVMAinsertion

50)

REFERENCES

[1].SvitlanaKULYK,etal.,Compoundsandmethodsformodulatingher2.PatentWO2024044570.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师