ChristinaWarinner_2012U[Christina Warinner][利用牙菌斑追踪古代疾病].pdfVIP

TED演讲者：CristinaWarinner|CristinaWarinner

演讲标题：CristinaWarinner:Trackingancientdiseasesusing...plaque|利用牙菌斑追踪古代疾病

内容概要：Imaginewatwecouldlearnaboutdiseasesbystudyingteistoryofuman

disease,fromancientominidstotepresent.Butow?TEDFellowCristinaWarinnerisan

acaeologicalgeneticist,andse.sfoundaspectacularnewtool--temicrobialDNAin

fossilizeddentalplaque.

CristinaWarinnerisaresearceratteUniversityofZuric,weresestudiesowumans

aveco-evolvedwitenvironments,dietsanddisease.

www.XiYuS锡育软件

Haveyoueverwonderedwhatisinsideyourdentalplaque?各位是否想過在各位的牙菌斑裡藏什麼?[00:12]

Probablynot,butpeoplelikemedo.可能沒有,但像我一樣的人[00:17]

ImanarcheologicalgeneticistattheCenterforEvolutionary我是一位考古學遺傳學家我任職於蘇黎世大學醫

MedicineattheUniversityofZurich,andIstudytheorigins藥發展中心我針對古人類骨骼和木乃伊遺骸進行

andevolutionofhumanhealthanddiseasebyconducting基因研究了解人類健康和疾病的起源和演化

geneticresearchontheskeletalandmummifiedremainsof[00:19]

ancienthumans.

Andthroughthiswork,Ihopetobetterunderstandthe透過此研究,我希望能更加了解我們的身體在進化

evolutionaryvulnerabilitiesofourbodies,sothatwecan上缺陷我們也得以改善並在未來控管我們的健康

improveandbettermanageourhealthinthefuture.狀況[00:33]

Therearedifferentwaystoapproachevolutionarymedicine,要改進研發醫藥有各種不同的方法其中一種就是

andonewayistoextracthumanDNAfromancientbones.從骨骼化石中提取人類的DNA[00:43]

Andfromtheseextracts,wecanreconstructthehuman從這些提取出的DNA我們可以重建不同時期的人

genomeatdifferentpointsintimeandlookforchangesthat類的基因組尋找可能因適應而產生的變化風險因

mightberelatedtoadaptations,riskfactorsandinerited素和遺傳疾病[00:50]

diseases.

plaque:n.匾;血小板;饰板geneticist:n.遗传学者Evo