黄芪和葶苈子加减治疗CHF的疗效及心脏彩超参数变化研究.docx

黄芪和葶苈子加减治疗CHF的疗效及心脏彩超参数变化研究

葛乐品林梅瑟姜祖超陈鹏鹏曹隆檬李焱

[关键词]?黄芪和葶苈子；慢性心力衰竭；临床疗效；心脏彩超

[中图分类号]?R541.6??????[文献标识码]?A??????[DOI]?10.3969/j.issn.1673-9701.2024.12.016

Study?on?the?effect?of?addition?or?subtraction?of?Astragalus?membranaceus?and?Draba?nemorosa?on?CHF?and?changes?of?cardiac?color?ultrasound?parameters

GE?Lepin，?LIN?Meise，?JIANG?Zuchao，?CHEN?Pengpeng，?CAO?Longmeng，?LI?Yan

Department?of?Cardiovascular?Diseases，?Wenzhou?Hospital?of?Traditional?Chinese?Medicine，?Wenzhou?325000，?Zhejiang，?China

[Abstract]?Objective?To?analyze?the?efficacy?of?Astragalus?membranaceus?and?Draba?nemorosa?in?the?treatment?of?chronic?heart?failure?（CHF），?the?change?of?cardiac?color?ultrasound?parameters?and?its?predictive?value?for?adverse?end?events.?Methods?A?total?of?92?patients?with?Qi-deficiency?and?blood-stasis?combined?with?Shuiyin?CHF?treated?in?Wenzhou?Hospital?of?Traditional?Chinese?Medicine?from?September?2019?to?September?2021?were?randomly?selected?and?divided?into?two?groups?by?random?number?table?method，?with?46?cases?in?each?group.?Patients?in?control?group?were?received?conventional?Western?medicine?treatment，?and?patients?in?observation?group?were?received?the?addition?and?subtraction?treatment?of?Yiqi?Huoxue?Lishui?prescription?based?on?Astragalus?membranaceus?and?Draba?nemorosa.?The?clinical?efficacy，?TCM?syndrome?score，?heart?color?ultrasound?parameters?and?the?incidence?of?adverse?endpoint?events?within?6?months?were?compared?between?the?two?groups.?Cardiac?color?doppler?ultrasound?parameters?were?compared?between?the?occurrence?group?and?the?non-occurrence?group，?and?receiver?operating?characteristic?curve?was?drawn?to?analyze?the?predictive?value?of?cardiac?color?Doppler?ultrasound?parameters?for?adverse?end?events.?Results?The?total?clinical?effective?rate?of?the?observation?group?（95.65%）?was?higher?than?that?of?the?control?group?（71.74%）?（P0.05）.?After?treatment，?palpitation，?weakness，?shortness?of?breath，?lethargy?and?lip?purple?score?in?observation?grou