MSRV-IN-1-生命科学试剂-MCE.pdf

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MSRV-IN-1

Cat.No.:HY-173338

CASNo.:1438403-50-9

分⼦式:C₁₈H₁₆N₂O₆

分⼦量:356.33

作⽤靶点:DNA/RNASynthesis

作⽤通路:CellCycle/DNADamage

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MSRV-IN-1(CompoundM3)是⼀种针对⽔⽣弹状病毒(如MSRV、SVCV和IHNV)的抑制剂，其抑制MSRV、

SVCV和IHNV的IC50分别为0.92μM、2.92μM和2.78μM。MSRV-IN-1并⾮直接作⽤于病毒粒⼦，⽽是

通过改变病毒诱导的细胞周期S期阻滞状态，破坏病毒复制环境，进⽽抑制病毒复制。以20mg/kg剂量腹腔

注射，MSRV-IN-1可使感染MSRV的⼤⼝⿊鲈存活率显著提升35.98%，并降低肝、脾、肾中的病毒载量。

MSRV-IN-1可⽤于⽔产养殖中弹状病毒相关疾病领域的研究[1]。

REFERENCES

[1].YangF,etal.Efficientantiviralactivityofanovelmagnololderivativeagainstaquaticrhabdoviruses[J].Aquaculture,2025,604:742464.

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