HF心衰英文课件.pptVIP

HF心衰英文课件

Heartfailure(HF)㈠MeaningofHF1.Conception:heartfailureisafinalcommonpathwayformanycardiacdisordersofdiverseetiologyandpathogenicmechanisms.Itisaclinicalsyndrome,manifestedasaresultoftheinabilityofthehearttomatchitsoutputtothemetabolicneedsofthebodyeventhoughthefillingpressureoftheheartisadequate.

中国心力衰竭流行病学推算我国目前成年人中约400万心衰患者随着年龄增加，心力衰竭患病率显著上升城市＞农村，北方＞南方，与我国冠心病和高血压的地区分布一致冠心病和高血压是心力衰竭的主要病因1.中华心血管病杂志2007;35(12):1076-95.2.顾东风等.中华心血管病杂志2003;31(1):3-6.

心力衰竭预后过去40年，心衰导致的死亡增加6倍（AHA2005）2007年中国心衰诊疗指南指出，有临床症状的患者5年生存率与恶性肿瘤相仿25%新发心力衰竭患者在1年内死亡(ESC1999）心力衰竭反复入院治疗很常见，超过50%患者半年内即再入院治疗(Krumholzetal.1997,Vinsonetal.1990,Burnsetal.1997)

狄兰.托马斯蒋介石伊丽莎白.泰勒聂荣臻叶利钦詹姆斯.门罗詹姆斯.布朗

”Twonewepidemicsofcardiovasculardiseaseareemerging:heartfailureandatrialfibrillation.”EugeneBraunwald NEJMNow1997心力衰竭——心脏疾病的最后战场EBraunwaldACC2003

2.HF=systolicHFand/ordiastolicHF3.HFandcardiacdysfunction(1)cardiacdysfunction=systolicdysfunctionordiastolicdysfunctionviainstrumentalexaminationwithoutsigns(2)HF=cardiacdysfunction+signs

TheDonkeyAnalogyVentriculardysfunctionlimitsapatientsabilitytoperformtheroutineactivitiesofdailyliving…Let’scompareourhearttothisdonkey,andourbodytothewagonthatthisdonkeyhastopulleveryday.

㈡Fundamentalcauses1.primarydecreasedmyocardialcontractilitysuchascoronarheartdisease(hungry)myocarditis,cardiomyopathy.(injury)

治疗

㈡Fundamentalcauses2.increasedburdenstotheheart①increasedafterload(pressureload):hypertensionaorticstenosispulmonarystenosispulmonaryhypertension.

㈡Fundamentalcauses②increasedpreload(volumeload):mitralincompetenceaorticincompetencetricuspidincompetenceatrialseptaldefect(ASD)ventricularseptaldefect(VSD)