膝骨关节炎临床康复指南诊断天津医院康复医学科李奇54课件.pptxVIP

膝骨关节炎临床康复指南（诊断）天津医院康复医学科李奇DepartmentofRehabilitationMedicine,TianjinHospitalLiQi

随着人口老龄化和肥胖程度的增加，骨关节炎成为致使老年人残疾的主要原因。OA患病率显著且不断增加社会负担，对个体、医疗系统和更为广泛的社会经济成本带来显著影响。Osteoarthritisistheleadingcauseofdisabilityinolderadultsasthepopulationagesandobesitylevelsincrease.TheprevalenceofOAisasignificantandgrowingburdenonsociety,withsignificantimpactsonindividuals,healthcaresystems,andbroadersocioeconomiccosts.关节炎成为仅次于高血压的老年患者第二大常见慢性病，膝骨关节炎已成为全球致残率的第四大疾病。Arthritisisthesecondmostcommonchronicdiseaseinolderpatientsafterhypertension,andosteoarthritisofthekneehasbecomethefourthmostdisablingdiseaseworldwide.发病率IncidenceofDisease

OA患病率OAprevalencerate≥75岁人群80%≥60岁人群50%40岁人群10%~17%发病率IncidenceofDisease

好发人群FavoredPopulation55岁以上的人群中25%的人膝关节至少每年会出现一次持续性的疼痛，60岁以上男性的发病率为21.5%，女性发病率则高达42.8%。因KOA引起疼痛的占10%，并且1/4的疼痛人群会出现残疾。Persistentkneepainoccursatleastonceayearin25%ofpeopleover55yearsofage,withaprevalenceof21.5%inmenover60yearsofageandupto42.8%inwomen.PainduetoKOAaccountsfor10%ofallcases,and1in4peoplewithpainwillbedisabled.

ZOA导致关节疼痛、畸形及功能活动受限，进而增加心血管疾病、糖尿病的发生率及全球死亡率。尤其是症状性KOA，研究发现可导致全因死亡率增加1倍。OAleadstojointpain,deformity,andlimitedfunctionalactivity,whichinturnincreasestheincidenceofcardiovasculardisease,diabetes,andglobalmortality.SymptomaticKOA,inparticular,hasbeenfoundtoleadtoaone-foldincreaseinall-causemortality.好发人群FavoredPopulation

相关性relevanceOA伴发疾病与全因死亡和严重心血管事件OAConcomitantDiseaseandAll-CauseMortalityandSeriousCardiovascularEvents患有心血管疾病且疼痛基线较高，死亡风险高Highriskofdeathwithcardiovasculardiseaseandhigherbaselinepain行动不便且先发性心血管疾病，发病率较高LimitedmobilityandpreexistingcardiovasculardiseasewithahighincidenceofOA残疾导致患者活动能力受限，心肺适应能力降低OAdisabilityresultsinlimitedmobilityandreducedcardiorespiratoryadaptationsforthepatient好发人群FavoredPopulation

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