抗苗勒管激素低水平人群行IVF_ICSI助孕效果分析.pdfVIP

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D01:10.3969/j.issn.10043845.2025.01.006

抗苗勒管激素低水平人群行IVF/ICSI助孕

效果分析

杨丽2，王雪松12，姜佳佳，王月莺1.2

慢性病管理研究所,济宁272000)

【摘要】目的分析抗苗勒管激素（AMH)低水平女性行1VF/ICSIET助孕的妊娠结局以及在不同年龄组内低AMH

期1VF/1CS1的396例患者的资料，按照AMH水平分为极低AMH组（AMH=0.5ng/ml，149例）和低AMH组（0.5ng/ml

AMH1.1ng/ml,247

181例)和高龄组（35岁，215例)两组，分析两组在极低AMH和低AMH条件下的妊娠结局和累计活产率。结果（1)极低

AMH和低AMH两组患者间不孕年限、基础雌二醇（E,）和基础孕酮（P)差异均无统计学意义（P0.05）；与低AMH组比

较,极低AMH组患者年龄更长、基础FSH和基础LH水平更高（P0.05）,促排卵过程中促性腺激素（Gn)用量更低、Gn天

数更短、获卵数更少（P0.05），累计活产率显著降低（P0.05）。（2)低龄组患者中低AMH组的获卵数显著高于极低

AMH组（P0.05),但妊娠结局差异均无统计学意义（P0.05）;高龄组患者中低AMH组的获卵数显著高于极低AMH组

（P0.05），且累计活产率也显著高于极低AMH组（P0.05）．结论在低AMH条件下（AMH1.1ng/ml)进行IVF/ICSl

助孕时，随着AMH水平的降低，累计活产率越低，高龄患者受影响程度更甚。

【关键词】抗苗勒管激素；辅助生殖技术；妊娠结局；累计活产率

【中图分类号】R711.6【文献标识码】A

Effectoflowanti-MullerianhormonelevelonpregnancyoutcomesinIVF/ICSI

YANGLi1-,WANGXue-songl-2,JIANGJia-jia,WANGYue-yingl.2

272000

1.DepartmentofReproductiveMedicine,JiningNo.1PeoplesHospital,Jining

2.JiningKeyLaboratoryofPregnancyDisorderResearch,Jining272000

3.InstituteforChronicDiseaseManagement,JiningAcademyofMedicalSciences,Jining272000

【Abstract]

Objective:Toanalyzetheeffectsoflowanti-Mullerianhormone(AMH)levelcombinedwithor

withouttheimpactofageonpregnancyoutcomesinIVF/ICSI-ET.

Methods:Atotalof396womenundergoingtheirfirstoocyteretrievalforIVF/ICSIwere

retrospectivelyanalyzedinJiningNo.1peopleshospitalfromJanuary2018toDecember2022.According

totheAMHlevel,patientsweredividedintotwogroups,theextremelylowAMHgroup(AMH0.5ng/ml,

149cases)andthelowAMHgroup(0.5ng/mlAMH1.1ng/ml,247cases),andbasiccharacteristics

andpregnancyoutcomeswerecomparedbetweenthetwogroups.Then,allofthepatientsweredivided

intotheyoungergroup(35yea