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- 2026-01-15 发布于上海
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Inhibitors•ScreeningLibraries•Proteins
www.MedChemE
4-Hydroxybicyclo[2.2.2]octane-1-carboxylicacid
Cat.No.:HY-35450
CASNo.:1127-13-5
分⼦式:C₉H₁₄O₃
分⼦量:170.21
作⽤靶点:PROTACLinkers
作⽤通路:PROTAC
储存⽅式:Storeatroomtemperature3years
*Insolvent:-80°C,6months;-20°C,1month(Storeatroom
temperature3years)
BIOLOGICALACTIVITY
⽣物活性4-Hydroxybicyclo[2.2.2]octane-1-carboxylicacid是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。
体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE389ubiquitinligase
andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto
selectivelydegradetargetproteins.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE
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