7-Boc-2-7-Diazaspiro-3-5-nonane-生命科学试剂-MCE.pdfVIP

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7-Boc-2-7-Diazaspiro-3-5-nonane-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

7-Boc-(2,7-Diazaspiro[3.5]nonane)

Cat.No.:HY-30755

CASNo.:896464-16-7

分⼦式:C₁₂H₂₂N₂O₂

分⼦量:226.32

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Powder-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性7-Boc-(2,7-Diazaspiro[3.5]nonane)是⼀种PROTAClinker,可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE449ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

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