新兴技术及理论在泌尿系统肿瘤“防诊治”中的应用：华西医院的临床经验分享.pdfVIP

448JModUrol,Vol.30No.5May2025

·综述·

新兴技术及理论在泌尿系统肿瘤“防诊治”中的应用：华西医院的临床经

验分享

曾斌，邱

下实，周翔鸿，曾浩，杨璐，魏强

（四川大学华西医院泌尿外科，泌尿外科研究所，四川成都610041）

Applicationofemergingtechnologiesandtheoriesintheprevention,diagnosis,and

treatmentofurinarysystemtumors:asummaryofclinicalexperienceinWestChina

Hospital

ZENGBin,QIUShi,ZHOUXianghong,ZENGHao,YANGLu,WEIQiang

(DepartmentofUrology,InstituteofUrologyandCenterofBiomedicalBigData,WestChinaHospital,

SichuanUniversity,Chengdu610041,China)

ABSTRACT:Urinarysystemtumorsareverycommonnowadays,includingprostatecancer,renalcancer,bladdercancer,and

urothelialcarcinoma.Inrecentyears,theincidenceofthesetumorshasbeenontherise.Thispaperbrieflysummarizesthe

emergingtechnologiesexploredbyWestChinaHospitalinrecentyearsforurinarysystemtumors,suchasgenesequencing

analysis,radiomicsandbigdata,liquidchromatography-massspectrometry,multi-modalintelligentfusiondiagnostictechnology,

surgicaldecision-makingtoolsbuiltwithartificialintelligenceandbigdata,mRNAvaccines,combinationoftargetedand

immunetherapies,andirreversibleelectroporationtechnology.Thesetechnologiesprovidestrongsupportandpointouttheways

fortheprevention,earlydiagnosis,andindividualizedtreatmentofurinarysystemtumors.

KEYWORDS:urinarysystemtumor;molecularpathologydiagnosis;mRNAvaccines;combinedtargetedandimmunotherapy;

WestChinaHospital;emergingtechnologies;prevention,diagnosisandtreatment

摘要：前列腺癌、肾癌、膀胱癌、尿路上皮癌等作为常见且高发的肿瘤类型，近年来发病率一直呈上升趋势。本文简要总结了华西

医院近年来在探索泌尿系统肿瘤新兴诊疗技术应用方面的经验，如基因测序分析、影像组学与大数据、液相色谱质谱联用技术、

多元智能融合诊断技术、人工智能与大数据构建的手术决策工具、mRNA疫苗、靶免联合治疗、不可逆电穿孔技术等，为泌尿系

肿瘤的预防、早期诊断及个性化治疗提供了强有力的技术支撑,并为未来相关疾病的研究和诊疗指明方向。

关键词：泌尿系统肿瘤；分子病理诊断；mRNA疫苗；靶免联合治疗；华西医院；新兴技术；防诊治

中图分类号：R691文献标志码：AD0I:10.3969/j.issn.1009-8291.2025.05.014