BPRCX-714-生命科学试剂-MCE.pdfVIP

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BPRCX714

Cat.No.:HY-177799

CASNo.:1892574-13-8

分⼦式:C₃₀H₅₁N₁₁O₃

分⼦量:613.8

作⽤靶点:CXCR

作⽤通路:GPCR/GProtein;Immunology/Inflammation

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性BPRCX714是⼀种CXCR4(CXC趋化因⼦受体4型)受体拮抗剂。BPRCX714可⽤于肝细胞癌的研究[1]。

IC50TargetCXCR4

体外研究BPRCX714exhibitsanIC50of34.2nMagainsttheCXCR4receptorinCCRF-CEMcells[1].

REFERENCES

[1].SongJS,etal.AhighlyselectiveandpotentCXCR4antagonistforhepatocellularcarcinomatreatment.ProcNatlAcadSciUSA.2021

Mar30;118(13):e2015433118.

[2].SongJS,etal.AhighlyselectiveandpotentCXCR4antagonistforhepatocellularcarcinomatreatment.ProcNatlAcadSciUSA.2021

Mar30;118(13):e2015433118.

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