BODIPY-581-591-C11-solution-生命科学试剂-MCE.pdfVIP

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BODIPY-581-591-C11-solution-生命科学试剂-MCE.pdf

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

BODIPY581/591C11(solution)

Cat.No.:HY-DY1022

CASNo.:217075-36-0

分⼦式:C₃₀H₃₅BF₂N₂O₂

分⼦量:504.43

作⽤靶点:Ferroptosis;FluorescentDye

作⽤通路:Apoptosis;Others

储存⽅式:-20°C,protectfromlight.Avoidrepeatedfreezingandthawing

*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light.Avoidrepeatedfreezingandthawing)

BIOLOGICALACTIVITY

⽣物活性BODIPY581/591C11(solution)是⼀种BODIPY氟硼荧衍⽣物,具有良好的光稳定性、低荧光伪影特质。

BODIPY581/591C11常⽤于活细胞内脂质过氧化和抗氧化性能的研究,或与羟基⾃由基反应、检测铁死亡(

ferroptosis)。BODIPY581/591C11本⾝为红⾊荧光(还原型;Ex=581nm,Em=591nm),与脂质结合后会产

⽣绿⾊荧光(氧化型;Ex=500nm,Em=510nm)。

溶剂及浓度:DMSO:2mM

体外研究Stocksolution

1.1PreparationofBODIPY581/591C11workingsolution

Dilutethestocksolutioninserum-freecellculturemediumorPBS.Thecorrespondingstocksolutioncanbe

dilutedaccordingtotheactualsituation.NotethatifthesolventisDMSO,thecytotoxicityofDMSOmustbe

considered,andasolventcontrolshouldbeprepared;ifthesolventispurewater,theworkingsolutionneeds

tobefilteredandsterilizedbeforeaddingcells.

Note:Pleaseadju

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