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- 2026-01-21 发布于上海
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Inhibitors•ScreeningLibraries•Proteins
www.MedChemE
BODIPY581/591C11(solution)
Cat.No.:HY-DY1022
CASNo.:217075-36-0
分⼦式:C₃₀H₃₅BF₂N₂O₂
分⼦量:504.43
作⽤靶点:Ferroptosis;FluorescentDye
作⽤通路:Apoptosis;Others
储存⽅式:-20°C,protectfromlight.Avoidrepeatedfreezingandthawing
*Insolvent:-80°C,6months;-20°C,1month(protectfrom
light.Avoidrepeatedfreezingandthawing)
BIOLOGICALACTIVITY
⽣物活性BODIPY581/591C11(solution)是⼀种BODIPY氟硼荧衍⽣物,具有良好的光稳定性、低荧光伪影特质。
BODIPY581/591C11常⽤于活细胞内脂质过氧化和抗氧化性能的研究,或与羟基⾃由基反应、检测铁死亡(
ferroptosis)。BODIPY581/591C11本⾝为红⾊荧光(还原型;Ex=581nm,Em=591nm),与脂质结合后会产
⽣绿⾊荧光(氧化型;Ex=500nm,Em=510nm)。
溶剂及浓度:DMSO:2mM
体外研究Stocksolution
1.1PreparationofBODIPY581/591C11workingsolution
Dilutethestocksolutioninserum-freecellculturemediumorPBS.Thecorrespondingstocksolutioncanbe
dilutedaccordingtotheactualsituation.NotethatifthesolventisDMSO,thecytotoxicityofDMSOmustbe
considered,andasolventcontrolshouldbeprepared;ifthesolventispurewater,theworkingsolutionneeds
tobefilteredandsterilizedbeforeaddingcells.
Note:Pleaseadju
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