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BP-1-102(Standard)

Cat.No.:HY-100493R

CASNo.:1334493-07-0

分⼦式:C₂₉H₂₇F₅N₂O₆S

分⼦量:626.59

作⽤靶点:STAT;ReferenceStandards

作⽤通路:JAK/STATSignaling;StemCell/Wnt;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性BP-1-102(Standard)是BP-1-102(HY-100493)的分析标准品。本产品⽤于研究及分析应⽤。BP-1-102是有⼝

服活性的转录因⼦Stat3的⼩分⼦抑制剂，其IC50值为6.8μM。

REFERENCES

[1].ZhangX,etal.Orallybioavailablesmall-moleculeinhibitoroftranscriptionfactorStat3regresseshumanbreastandlungcancer

xenografts.ProcNatlAcadSciUSA.2012Jun12;109(24):9623-8.

[2].DeSimoneV,etal.Th17-typecytokines,IL-6andTNF-αsynergisticallyactivateSTAT3andNF-kBtopromotecolorectalcancercell

growth.Oncogene.2015Jul;34(27):3493-503.

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