DCM-ONOO-生命科学试剂-MCE.pdfVIP

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DCM–ONOO

Cat.No.:HY-D2968

CASNo.:2759816-87-8

分⼦式:C₃₂H₂₂N₃O₂P

分⼦量:511.51

作⽤靶点:FluorescentDye

作⽤通路:Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性DCM-ONOO是⼀种近红外双光⼦荧光探针,专为实时监测癫痫模型中过氧亚硝酸盐(ONOO)的动态波动⽽

设计。DCM-ONOO表现出优异的光学性能,单光⼦激发(Ex)为520nm;单光⼦发射(Em)为685nm;双光

⼦激发为820nm;斯托克斯位移为165nm。DCM-ONOO加⼊ONOO从460nm红移⾄512nm,且仅对

ONOO产⽣显著荧光响应。DCM-ONOO成功应⽤于⼤⿏癫痫模型。

REFERENCES

[1].LuoX,etal.IndicationofDynamicPeroxynitriteFluctuationsintheRatEpilepsyModelwithaNear-InfraredTwo-PhotonFluorescent

Probe.AnalChem.2021Feb2;93(4):2490-2499.

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