MC-Phe-Lys-MMT-PABOH-生命科学试剂-MCE.pdfVIP

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MC-Phe-Lys(MMT)-PABOH

Cat.No.:HY-153212

CASNo.:159857-65-5

分⼦式:C₅₂H₅₇N₅O₇

分⼦量:864.04

作⽤靶点:DrugIntermediate

作⽤通路:Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MC-Phe-Lys(MMT)-PABOH是⼀个连接⼦。MC-Phe-Lys(MMT)-PABOH可⽤于合成免疫缀合物BR96-Phe-Lys-

PABC-DOX。MC-Phe-Lys(MMT)-PABOH可⽤于结肠癌、卵巢癌研究。

REFERENCES

[1].DubowchikGM,etal.CathepsinB-labiledipeptidelinkersforlysosomalreleaseofdoxorubicinfrominternalizingimmunoconjugates:

modelstudiesofenzymaticdrugreleaseandantigen-specificinvitroanticanceractivity.BioconjugChem.2002Jul-Aug;13(4):855-69.

[2].YaoH,etal.MethodstoDesignandSynthesizeAntibody-DrugConjugates(ADCs).IntJMolSci.2016Feb2;17(2):194.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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