M2I-1-Standard-生命科学试剂-MCE.pdfVIP

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M2I-1(Standard)

Cat.No.:HY-100341R

CASNo.:312271-03-7

分⼦式:C₁₉H₂₄N₄O₄S

分⼦量:404.48

作⽤靶点:CheckpointKinase(Chk);ReferenceStandards

作⽤通路:CellCycle/DNADamage;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性M2I-1(Standard)是M2I-1(HY-100341)的分析标准品。本产品⽤于研究及分析应⽤。M2I-1是⼀种Mad2抑

制剂，靶向Mad2与Cdc20的结合，Mad2与Cdc20结合是纺锤体装配检查点(SAC)内必不可少的蛋⽩-蛋⽩

相互作⽤(PPI)[1]。

IC50TargetMad2[1]

REFERENCES

[1].JohannaKastletal.Mad2Inhibitor-1(M2I-1):ASmallMoleculeProtein-ProteinInteractionInhibitorTargetingtheMitoticSpindle

AssemblyCheckpoint.ACSChem.Biol.,2015,10(7),pp1661-1666.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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