MDL-72527-Standard-生命科学试剂-MCE.pdfVIP

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MDL72527(Standard)

Cat.No.:HY-100621R

CASNo.:93565-01-6

分⼦式:C₁₂H₂₂Cl₂N₂

分⼦量:265.22

作⽤靶点:MonoamineOxidase;ReferenceStandards

作⽤通路:NeuronalSignaling;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性MDL72527(Standard)是MDL72527(HY-100621)的分析标准品。本产品⽤于研究及分析应⽤。MDL72527

是⼀种有效的多胺氧化酶(polyamineoxidase(PAO))抑制剂。MDL72527显⽰出溶酶体效应。MDL72527具

有神经保护作⽤[1][2]。

IC50Targetpolyamineoxidase(PAO)[1]

REFERENCES

[1].DoğanA,etal.EffectsofMDL72527,aspecificinhibitorofpolyamineoxidase,onbrainedema,ischemicinjuryvolume,andtissue

polyaminelevelsinratsaftertemporarymiddlecerebralarteryocclusion.JNeurochem.1999Feb;72(2):765-70.

[2].AgostinelliE,etal.Toxicityofenzymaticoxidationproductsofsperminetohumanmelanomacells(M14):sensitizationbyheatandMDL

72527.BiochimBiophysActa.2006Oct;1763(10):1040-50.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.