NCATS-SM7270-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

NCATS-SM7270

Cat.No.:HY-173096

分⼦式:C₂₃H₂₂N₆O₂S

分⼦量:446.52

作⽤靶点:NADPHOxidase

作⽤通路:MetabolicEnzyme/Protease

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性NCATS-SM7270是⼀种⾼度特异性的NOX2抑制剂,其IC50为4.09μM。NCATS-SM7270可保护⼩⿏免受

轻度创伤性脑损伤。

IC50TargetNOX2

4.09μM(IC50)

REFERENCES

[1].MasonH,etal.DevelopmentofanimprovedandspecificinhibitorofNADPHoxidase2totreattraumaticbraininjury.RedoxBiol.2023

Apr;60:102611.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师

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