NCR-631-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

NCR631

Cat.No.:HY-177986

CASNo.:160911-12-6

分⼦式:C₇H₅Br₂NO₃

分⼦量:310.93

作⽤靶点:DrugDerivative

作⽤通路:Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性NCR631是⼀种3-HAO抑制剂和3-hydroxyanthranilicacid(HY-W001171)类似物。NCR-631具有抗惊厥特

性。NCR-631对缺氧表现出浓度依赖性的保护作⽤。

REFERENCES

[1].LuthmanJ.Anticonvulsanteffectsofthe3-hydroxyanthranilicaciddioxygenaseinhibitorNCR-631.AminoAcids.2000;19(1):325-34.

[2].LuthmanJ,etal.Effectsofthe3-hydroxyanthranilicacidanalogueNCR-631onanoxia-,IL-1beta-andLPS-inducedhippocampal

pyramidalcelllossinvitro.AminoAcids.1998;14(1-3):263-9.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师