N-Cholyl-L-glutamic-acid-GluCA-生命科学试剂-MCE.pdfVIP

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N-Cholyl-L-glutamicacid

Cat.No.:HY-176967

CASNo.:23828-78-6

Synonyms:GluCA

分⼦式:C₂₉H₄₇NO₈

分⼦量:537.69

作⽤靶点:DrugDerivative;PregnaneXReceptor(PXR)

作⽤通路:Others;VitaminDRelated/NuclearReceptor

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性N-Cholyl-L-glutamicacid是Cholicacid(HY-N0324)与L-glutamicacid(HY-14608)的结合物。N-Cholyl-L-

glutamicacid能增加PXR及其下游靶基因Cyp3a11的表达。N-Cholyl-L-glutamicacid可⽤于克罗恩病的研

究。

REFERENCES

[1].GentryEC,etal.Reversemetabolomicsforthediscoveryofchemicalstructuresfromhumans.Nature.2024Feb;626(7998):419-426.

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