R-FTY720-OMe-生命科学试剂-MCE.pdfVIP

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(R)-FTY720-OMe

Cat.No.:HY-12897

CASNo.:1382486-90-9

分⼦式:C₂₀H₃₅NO₂

分⼦量:321.5

作⽤靶点:SphK

作⽤通路:Immunology/Inflammation

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性(R)-FTY720-OMe是⼀种选择性SphK2抑制剂，其IC50为16.5μM。(R)-FTY720-OMe可⽤于癌症、纤维化

、阿尔茨海默病和镰状细胞病的研究[1]。

IC50TargetSphK2

16.5μM(IC50)

REFERENCES

[1].CongdonMD,etal.Structure-ActivityRelationshipStudiesandMolecularModelingofNaphthalene-BasedSphingosineKinase2

Inhibitors.ACSMedChemLett.2016Feb2;7(3):229-34.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师