Sebaconitrile-生命科学试剂-MCE.pdfVIP

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Sebaconitrile

Cat.No.:HY-W130919

CASNo.:1871-96-1

分⼦式:C₁₀H₁₆N₂

分⼦量:164.25

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性Sebaconitrile是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE816ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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