Selenotifen-BN-52256-生命科学试剂-MCE.pdfVIP

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Inhibitors•ScreeningLibraries•Proteins

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Selenotifen

Cat.No.:HY-116481

CASNo.:135472-91-2

Synonyms:BN52256

分⼦式:C₁₉H₁₉NOS

分⼦量:356.32

作⽤靶点:Platelet-activatingFactorReceptor(PAFR)

作⽤通路:GPCR/GProtein

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Selenotifen(BN52256)是⼀种抗过敏剂。Selenotifen是PAF受体的强效拮抗剂。Selenotifen具有统计学意

义上的抗⼼律失常作⽤[1][2]。

REFERENCES

[1].MaySW,etal.Selenium-basedantihypertensives.Rationaleandpotential.Drugs.1998Dec;56(6):959-64.

[2].MestHJ,etal.EffectofBN52256andothermediatorantagonistsonouabain-inducedcardiacarrhythmiainamodelofanaphylaxisin

guinea-pigs.PharmacolRes.1992Feb-Mar;25(2):173-80.

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